Info
| ID | 2194 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 1 |
| Donor atoms | {"N": 3, "P": 1} |
| Abbreviation | 5 |
| SMILES | [Cl-].c1ccc(Nc2ccccc2)cc1.c1ccc(P(c2ccccc2)c2ccccc2)cc1.c1cnc2c(c1)ccc1cccnc12 |
TUCAN
C42H34N3PRu/(1-49)(2-37)(3-38)(4-35)(5-45)(6-55)(7-41)(8-43)(9-62)(10-68)(11-52)(12-40)(13-51)(14-69)(15-39)(16-48)(17-44)(18-47)(19-42)(20-50)(21-36)(22-61)(23-60)(24-53)(25-65)(26-56)(27-64)(28-63)(29-54)(30-59)(31-57)(32-58)(33-46)(34-77)(35-37)(35-43)(36-52)(36-68)(37-74)(38-39)(38-74)(39-43)(40-44)(40-75)(41-42)(41-45)(42-47)(44-48)(45-70)(46-54)(46-59)(47-55)(48-50)(49-62)(49-66)(50-51)(51-75)(52-66)(53-60)(53-76)(54-57)(55-70)(56-65)(56-76)(57-72)(58-59)(58-72)(60-64)(61-63)(61-69)(62-67)(63-67)(64-65)(66-71)(67-73)(68-78)(69-79)(70-77)(71-73)(71-78)(72-77)(73-79)(74-80)(75-80)(76-80)(78-81)(79-81)(80-81)
Measurements (2)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| MDA-MB-231 | 3.3 | — | 10.1016/j.jinorgbio.2019.01.00... | 2019 |
| V79 | — | — | 10.1016/j.jinorgbio.2019.01.00... | 2019 |
🧬 Cell Death Types (1)
Apoptosis
medium
«There were more round cells, when compared to the control cells, which is indicative of cell detachment, probably due to apoptotic cell death.»