Info
| ID | 2193 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 1 |
| Donor atoms | {"N": 3, "P": 1} |
| Abbreviation | 4 |
| SMILES | Cc1ccc(-c2ccc(C)cn2)nc1.[Cl-].c1ccc(Nc2ccccc2)cc1.c1ccc(P(c2ccccc2)c2ccccc2)cc1 |
TUCAN
C42H38N3PRu/(1-55)(2-52)(3-41)(4-53)(5-51)(6-42)(7-50)(8-59)(9-60)(10-39)(11-39)(12-45)(13-49)(14-63)(15-58)(16-61)(17-43)(18-46)(19-67)(20-56)(21-39)(22-72)(23-40)(24-73)(25-48)(26-64)(27-62)(28-65)(29-68)(30-66)(31-69)(32-47)(33-44)(34-54)(35-40)(36-40)(37-57)(38-81)(39-70)(40-71)(41-52)(41-78)(42-53)(42-78)(43-45)(43-55)(44-47)(44-74)(45-76)(46-49)(46-55)(47-70)(48-56)(48-67)(49-76)(50-58)(50-79)(51-52)(51-53)(54-57)(54-71)(56-77)(57-75)(58-63)(59-61)(59-79)(60-62)(60-80)(61-63)(62-64)(64-65)(65-66)(66-80)(67-69)(68-69)(68-77)(70-72)(71-73)(72-82)(73-83)(74-75)(74-82)(75-83)(76-81)(77-81)(78-84)(79-84)(80-84)(82-85)(83-85)(84-85)
Measurements (2)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| MDA-MB-231 | 2.4 | — | 10.1016/j.jinorgbio.2019.01.00... | 2019 |
| V79 | 9.9 | — | 10.1016/j.jinorgbio.2019.01.00... | 2019 |
🧬 Cell Death Types (1)
Apoptosis
medium
«There were more round cells, when compared to the control cells, which is indicative of cell detachment, probably due to apoptotic cell death.»