Info
| ID | 2192 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 1 |
| Donor atoms | {"N": 3, "P": 1} |
| Abbreviation | 3 |
| SMILES | [Cl-].c1ccc(-c2ccccn2)nc1.c1ccc(Nc2ccccc2)cc1.c1ccc(P(c2ccccc2)c2ccccc2)cc1 |
TUCAN
C40H34N3PRu/(1-42)(2-38)(3-41)(4-43)(5-53)(6-55)(7-56)(8-66)(9-49)(10-40)(11-46)(12-35)(13-39)(14-44)(15-51)(16-62)(17-47)(18-60)(19-61)(20-67)(21-65)(22-54)(23-36)(24-58)(25-59)(26-63)(27-57)(28-37)(29-45)(30-50)(31-48)(32-52)(33-64)(34-75)(35-38)(35-39)(36-44)(36-54)(37-58)(37-59)(38-42)(39-43)(40-41)(40-68)(41-47)(42-72)(43-72)(44-53)(45-49)(45-50)(46-51)(46-68)(47-51)(48-52)(48-64)(49-66)(50-69)(52-67)(53-73)(54-55)(55-73)(56-58)(56-74)(57-59)(57-74)(60-62)(60-71)(61-62)(61-65)(63-65)(63-71)(64-70)(66-76)(67-77)(68-75)(69-70)(69-76)(70-77)(71-75)(72-78)(73-78)(74-78)(76-79)(77-79)(78-79)
Measurements (2)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| MDA-MB-231 | 4.2 | — | 10.1016/j.jinorgbio.2019.01.00... | 2019 |
| V79 | 27 | — | 10.1016/j.jinorgbio.2019.01.00... | 2019 |
🧬 Cell Death Types (1)
Apoptosis
medium
«There were more round cells, when compared to the control cells, which is indicative of cell detachment, probably due to apoptotic cell death.»