Info
| ID | 2191 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 1 |
| Donor atoms | {"N": 3, "P": 1} |
| Abbreviation | 2 |
| SMILES | NCCN.[Cl-].c1ccc(Nc2ccccc2)cc1.c1ccc(P(c2ccccc2)c2ccccc2)cc1 |
TUCAN
C32ClN3PRu/(1-2)(1-4)(2-3)(3-6)(4-30)(5-11)(5-18)(6-30)(7-8)(7-28)(8-13)(9-11)(9-19)(10-21)(10-24)(12-14)(12-28)(13-14)(15-16)(15-29)(16-17)(17-25)(18-31)(19-31)(20-25)(20-29)(21-32)(22-23)(22-32)(23-24)(26-27)(26-33)(27-34)(28-35)(29-35)(30-36)(31-36)(32-36)
Measurements (2)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| MDA-MB-231 | 26 | — | 10.1016/j.jinorgbio.2019.01.00... | 2019 |
| V79 | — | — | 10.1016/j.jinorgbio.2019.01.00... | 2019 |
🧬 Cell Death Types (1)
Apoptosis
medium
«There were more round cells, when compared to the control cells, which is indicative of cell detachment, probably due to apoptotic cell death.»