Info
| ID | 2190 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 1 |
| Donor atoms | {"N": 2, "P": 1} |
| Abbreviation | 1 |
| SMILES | [Cl-].c1ccc(Nc2ccccc2)cc1.c1ccc(Nc2ccccc2)cc1.c1ccc(P(c2ccccc2)c2ccccc2)cc1 |
TUCAN
C42ClN2PRu/(1-2)(1-5)(2-40)(3-9)(3-11)(4-10)(4-11)(5-7)(6-7)(6-40)(8-18)(8-26)(9-36)(10-36)(12-13)(12-16)(13-37)(14-15)(14-16)(15-37)(17-22)(17-24)(18-20)(19-27)(19-35)(20-28)(21-23)(21-24)(22-38)(23-38)(25-30)(25-34)(26-41)(27-29)(28-41)(29-42)(30-39)(31-35)(31-42)(32-33)(32-34)(33-39)(36-43)(37-43)(38-44)(39-44)(40-45)(41-45)(42-45)
Measurements (2)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| MDA-MB-231 | 5.7 | — | 10.1016/j.jinorgbio.2019.01.00... | 2019 |
| V79 | — | — | 10.1016/j.jinorgbio.2019.01.00... | 2019 |
🧬 Cell Death Types (1)
Apoptosis
medium
«There were more round cells, when compared to the control cells, which is indicative of cell detachment, probably due to apoptotic cell death.»