Info
| ID | 2048 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 2 |
| Donor atoms | {"N": 6} |
| Abbreviation | Ru(phen)2(Hecip) |
| SMILES | CCn1c2ccccc2c2cc(-c3nc4c5cccnc5c5ncccc5c4[nH]3)ccc21.c1cnc2c(c1)ccc1cccnc12.c1cnc2c(c1)ccc1cccnc12 |
TUCAN
C51H35N9Ru/(1-75)(2-69)(3-44)(4-75)(5-43)(6-53)(7-38)(8-70)(9-73)(10-37)(11-42)(12-39)(13-47)(14-40)(15-48)(16-56)(17-36)(18-36)(19-36)(20-49)(21-71)(22-57)(23-52)(24-72)(25-74)(26-51)(27-50)(28-41)(29-45)(30-58)(31-59)(32-46)(33-54)(34-55)(35-88)(36-75)(37-55)(37-60)(38-40)(38-60)(39-41)(39-63)(40-69)(41-66)(42-48)(42-63)(43-47)(43-71)(44-59)(44-79)(45-46)(45-72)(46-61)(47-62)(48-70)(49-51)(49-73)(50-54)(50-74)(51-66)(52-58)(52-65)(53-56)(53-83)(54-67)(55-67)(56-64)(57-64)(57-68)(58-59)(60-76)(61-81)(61-85)(62-80)(62-84)(63-77)(64-86)(65-68)(65-79)(66-78)(67-82)(68-83)(69-90)(70-91)(71-87)(72-95)(73-92)(74-94)(75-89)(76-82)(76-90)(77-78)(77-91)(78-92)(79-89)(80-81)(80-88)(81-93)(82-94)(83-89)(84-85)(84-87)(85-95)(86-88)(86-93)(90-96)(91-96)(92-96)(93-96)(94-96)(95-96)
Measurements (4)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| SK-BR-3 | 8.6 | — | 10.1371/journal.pone.0096082 | 2014 |
| A549 | 9.6 | — | 10.1371/journal.pone.0096082 | 2014 |
| BEL-7402 | 11 | — | 10.1371/journal.pone.0096082 | 2014 |
| MG-63 | 15 | — | 10.1371/journal.pone.0096082 | 2014 |
🧬 Cell Death Types (1)
Apoptosis
high
«The apoptotic study indicates that complexes 1 and 2 can effectively induce apoptosis of BEL-7402 cells and inhibit the proliferation in the G0/G1 phase on BEL-7402 cells. Additionally, complexes 1 an...»