Info
| ID | 2047 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 2 |
| Donor atoms | {"N": 8} |
| Abbreviation | 2 |
| SMILES | O=Cc1c2ccccc2c(-c2nc3c4cccnc4c4ncccc4c3[nH]2)c2ccccc12.c1cnc2c(c1)ccc1cccnc12.c1cnc2c(c1)ccc1cccnc12 |
TUCAN
C52H32N8ORu/(1-69)(2-36)(3-52)(4-40)(5-84)(6-41)(7-38)(8-33)(9-37)(10-34)(11-70)(12-39)(13-44)(14-72)(15-35)(16-46)(17-45)(18-51)(19-47)(20-54)(21-42)(22-43)(23-49)(24-50)(25-55)(26-56)(27-53)(28-73)(29-71)(30-74)(31-48)(32-86)(33-37)(33-69)(34-39)(34-70)(35-47)(35-72)(36-38)(36-57)(37-57)(38-58)(39-58)(40-44)(40-46)(41-46)(41-65)(42-45)(42-50)(43-49)(43-61)(44-59)(45-60)(47-63)(48-54)(48-64)(49-73)(50-53)(51-52)(51-66)(52-71)(53-68)(54-74)(55-56)(55-63)(56-64)(57-75)(58-76)(59-62)(59-65)(60-62)(60-68)(61-77)(61-82)(62-84)(63-79)(64-80)(65-67)(66-78)(66-81)(67-68)(67-83)(69-87)(70-89)(71-88)(72-91)(73-85)(74-92)(75-76)(75-87)(76-89)(77-81)(77-86)(78-82)(78-88)(79-80)(79-91)(80-92)(81-90)(82-85)(83-86)(83-90)(84-93)(87-94)(88-94)(89-94)(90-94)(91-94)(92-94)
Measurements (4)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| SK-BR-3 | 4.1 | — | 10.1371/journal.pone.0096082 | 2014 |
| BEL-7402 | 11 | — | 10.1371/journal.pone.0096082 | 2014 |
| A549 | 13 | — | 10.1371/journal.pone.0096082 | 2014 |
| MG-63 | 18 | — | 10.1371/journal.pone.0096082 | 2014 |
🧬 Cell Death Types (1)
Apoptosis
high
«The apoptotic study indicates that complexes 1 and 2 can effectively induce apoptosis of BEL-7402 cells and inhibit the proliferation in the G0/G1 phase on BEL-7402 cells. Additionally, complexes 1 an...»