Info
| ID | 2046 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 2 |
| Donor atoms | {"N": 8} |
| Abbreviation | 1 |
| SMILES | O=Cc1c2ccccc2c(-c2nc3c4cccnc4c4ncccc4c3[nH]2)c2ccccc12.c1ccc(-c2ccccn2)nc1.c1ccc(-c2ccccn2)nc1 |
TUCAN
C48H32N8ORu/(1-65)(2-33)(3-50)(4-39)(5-80)(6-70)(7-36)(8-66)(9-34)(10-49)(11-35)(12-37)(13-40)(14-38)(15-69)(16-42)(17-51)(18-56)(19-41)(20-67)(21-46)(22-43)(23-68)(24-55)(25-53)(26-52)(27-54)(28-44)(29-45)(30-47)(31-48)(32-82)(33-36)(33-74)(34-36)(34-65)(35-44)(35-66)(37-43)(37-75)(38-43)(38-67)(39-40)(39-42)(40-49)(41-56)(41-60)(42-57)(44-46)(45-47)(45-48)(46-76)(47-77)(48-68)(49-62)(50-51)(50-61)(51-70)(52-53)(52-54)(53-64)(54-55)(55-58)(56-69)(57-62)(57-63)(58-63)(58-64)(59-62)(59-64)(59-79)(60-72)(60-73)(61-71)(61-78)(63-80)(65-83)(66-84)(67-85)(68-86)(69-88)(70-81)(71-73)(71-81)(72-78)(72-87)(73-88)(74-75)(74-83)(75-85)(76-77)(76-84)(77-86)(78-82)(79-82)(79-87)(80-89)(83-90)(84-90)(85-90)(86-90)(87-90)(88-90)
Measurements (4)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| SK-BR-3 | 9.4 | — | 10.1371/journal.pone.0096082 | 2014 |
| BEL-7402 | 9.8 | — | 10.1371/journal.pone.0096082 | 2014 |
| A549 | 20 | — | 10.1371/journal.pone.0096082 | 2014 |
| MG-63 | 20 | — | 10.1371/journal.pone.0096082 | 2014 |
🧬 Cell Death Types (1)
Apoptosis
high
«The apoptotic study indicates that complexes 1 and 2 can effectively induce apoptosis of BEL-7402 cells and inhibit the proliferation in the G0/G1 phase on BEL-7402 cells. Additionally, complexes 1 an...»