home← all complexes Ir builderC^N familiesD-MPNN

Complex #1811 — Ru(2) [9]

2D Structure

Structure
⬇ MOL V3000

Info

ID1811
MetalRu
Oxidation state2
Charge1
Donor atoms{"N": 1}
Abbreviation9
SMILESCc1c(C)c(C)[c-](C)c1C.Nc1ccccc1

TUCAN

C16NRu/(1-11)(2-12)(3-13)(4-14)(5-15)(6-7)(6-16)(7-10)(8-9)(8-16)(9-10)(11-12)(11-13)(12-14)(13-15)(14-15)(16-17)

Measurements (25)

Cell lineIC₅₀ dark (µM)IC₅₀ light (µM)DOIYear
MM96L3.5— 10.1002/asia.201100637 2012
MM96L3.5— 10.1021/ic801159f 2008
CI80-13S4.5— 10.1002/asia.201100637 2012
MCF-74.7— 10.1002/asia.201100637 2012
MCF-74.7— 10.1021/ic801159f 2008
MM96L6.1— 10.1021/ic801159f 2008
T47D9.1— 10.1002/asia.201100637 2012
MM96L9.3— 10.1021/ic801159f 2008
MM418c510— 10.1002/asia.201100637 2012
MCF-711— 10.1021/ic801159f 2008
MDA-MB-23112— 10.1002/asia.201100637 2012
MDA-MB-23112— 10.1021/ic801159f 2008
DU-14512— 10.1002/asia.201100637 2012
MCF-713— 10.1021/ic801159f 2008
PC-314— 10.1002/asia.201100637 2012
MDA-MB-23125— 10.1021/ic801159f 2008
RAW 264.727— 10.1002/asia.201100637 2012
MDA-MB-23131— 10.1021/ic801159f 2008
A54936— 10.1002/asia.201100637 2012
B1636— 10.1002/asia.201100637 2012
HT-2938— 10.1002/asia.201100637 2012
NFF98— 10.1002/asia.201100637 2012
NFF98— 10.1021/ic801159f 2008
NFF1.8e+02— 10.1021/ic801159f 2008
NFF1.9e+02— 10.1021/ic801159f 2008

🧬 Cell Death Types (1)

Apoptosis high
«Mechanistic studies revealed that all complexes caused apoptosis induction by activating caspases with upregulation of Bax and downregulation of Bcl-2.»

Source-assisted 2D generator

Builds the drawing from source ligand graphs and explicit donor metadata, then uses Metal2D only for layout. Publication output uses black bonds without arrows or colour highlighting; validated octahedral enantiomers are encoded directly with solid and hashed wedge bonds.

experimental validation surface
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The generated SVG will appear here. The legacy ligand image above stays visible for side-by-side review.