home← all complexes Ir builderC^N familiesD-MPNN

Complex #1810 — Ru(2) [8]

2D Structure

Structure
⬇ MOL V3000

Info

ID1810
MetalRu
Oxidation state2
Charge1
Donor atoms{"O": 1}
Abbreviation8
SMILESCCCC(=O)c1ccccc1.Cc1c(C)c(C)[c-](C)c1C

TUCAN

C20ORu/(1-15)(2-16)(3-17)(4-18)(5-19)(6-12)(7-10)(7-14)(8-10)(8-11)(9-11)(9-14)(12-13)(13-20)(14-20)(15-16)(15-17)(16-18)(17-19)(18-19)(20-21)

Measurements (25)

Cell lineIC₅₀ dark (µM)IC₅₀ light (µM)DOIYear
T47D1.8— 10.1002/asia.201100637 2012
MM96L2.9— 10.1002/asia.201100637 2012
MM96L2.9— 10.1021/ic801159f 2008
CI80-13S2.9— 10.1002/asia.201100637 2012
MCF-73— 10.1002/asia.201100637 2012
MCF-73— 10.1021/ic801159f 2008
PC-33.9— 10.1002/asia.201100637 2012
HT-294— 10.1002/asia.201100637 2012
DU-1454.3— 10.1002/asia.201100637 2012
MM418c55.2— 10.1002/asia.201100637 2012
MM96L6.8— 10.1021/ic801159f 2008
MM96L7.2— 10.1021/ic801159f 2008
B168.6— 10.1002/asia.201100637 2012
MDA-MB-2319.1— 10.1002/asia.201100637 2012
MDA-MB-2319.1— 10.1021/ic801159f 2008
A5499.7— 10.1002/asia.201100637 2012
MCF-711— 10.1021/ic801159f 2008
MCF-717— 10.1021/ic801159f 2008
MDA-MB-23130— 10.1021/ic801159f 2008
RAW 264.730— 10.1002/asia.201100637 2012
MDA-MB-23132— 10.1021/ic801159f 2008
NFF33— 10.1002/asia.201100637 2012
NFF33— 10.1021/ic801159f 2008
NFF1.3e+02— 10.1021/ic801159f 2008
NFF1.4e+02— 10.1021/ic801159f 2008

🧬 Cell Death Types (1)

Apoptosis high
«Mechanistic studies revealed that all complexes caused apoptosis induction by activating caspases with upregulation of Bax and downregulation of Bcl-2.»

Source-assisted 2D generator

Builds the drawing from source ligand graphs and explicit donor metadata, then uses Metal2D only for layout. Publication output uses black bonds without arrows or colour highlighting; validated octahedral enantiomers are encoded directly with solid and hashed wedge bonds.

experimental validation surface
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The generated SVG will appear here. The legacy ligand image above stays visible for side-by-side review.