Info
| ID | 1803 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 1 |
| Donor atoms | {"N": 5} |
| Abbreviation | 4c |
| SMILES | O=C1Cc2c([nH]c3ccc(/N=C/c4ccccn4)cc23)-c2ccccc2N1.O=Cc1ccc(OCC(=O)NCc2ccccc2)cc1.[Cl-] |
TUCAN
C38H31N5O4Ru/(1-37)(2-66)(3-59)(4-33)(5-65)(6-58)(7-46)(8-42)(9-41)(10-43)(11-39)(12-51)(13-50)(14-35)(15-34)(16-48)(17-66)(18-36)(19-32)(20-38)(21-59)(22-44)(23-40)(24-45)(25-57)(26-47)(27-49)(28-51)(29-72)(30-70)(31-71)(32-34)(32-67)(33-37)(33-46)(34-52)(35-39)(35-46)(36-38)(36-52)(37-56)(38-67)(39-56)(40-41)(40-61)(41-43)(42-44)(42-49)(43-58)(44-53)(45-50)(45-64)(47-54)(47-64)(48-49)(48-62)(50-63)(51-55)(51-69)(52-65)(53-60)(53-62)(54-55)(54-63)(55-60)(56-59)(57-61)(57-73)(58-74)(59-70)(60-71)(61-74)(62-72)(63-71)(64-73)(65-76)(66-68)(66-78)(67-78)(68-70)(68-75)(69-72)(69-77)(73-79)(74-79)(78-79)
Measurements (5)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| CH-1 | 55 | — | 10.1021/ic201801e | 2011 |
| SW480 | 1.8e+02 | — | 10.1021/ic201801e | 2011 |
| A549 | — | — | 10.1021/ic201801e | 2011 |
| A2780 | — | — | 10.1021/ic201801e | 2011 |
| A2780cisR | — | — | 10.1021/ic201801e | 2011 |
🧬 Cell Death Types (1)
Apoptosis
medium
«the appearance of a pronounced sub-G1/G0 fraction (excluded from analysis) and the tremendous decrease of the G2/M fraction (27 ± 6%) at this highest concentration suggest that apoptotic cell death is...»