Info
| ID | 1800 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 1 |
| Donor atoms | {"N": 6} |
| Abbreviation | 1c |
| SMILES | O=Cc1ccc(OCC(=O)NCc2ccccc2)cc1.[Cl-].c1ccc2[nH]c(-c3n[nH]c4ncccc34)nc2c1 |
TUCAN
C29H24N6O3Ru/(1-34)(2-27)(3-25)(4-35)(5-26)(6-39)(7-44)(8-51)(9-28)(10-30)(11-50)(12-38)(13-44)(14-32)(15-33)(16-43)(17-29)(18-31)(19-36)(20-37)(21-51)(22-56)(23-55)(24-57)(25-36)(25-47)(26-33)(26-46)(27-29)(27-52)(28-30)(28-39)(29-41)(30-42)(31-32)(31-39)(32-42)(33-36)(34-35)(34-43)(35-40)(37-38)(37-41)(38-52)(40-45)(40-49)(41-50)(42-44)(43-58)(44-56)(45-48)(45-59)(46-47)(46-55)(47-54)(48-54)(48-55)(49-57)(49-58)(50-61)(51-53)(51-62)(52-62)(53-56)(53-60)(57-59)(58-63)(59-63)(62-63)
Measurements (5)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| CH-1 | 1.4e+02 | — | 10.1021/ic201801e | 2011 |
| SW480 | — | — | 10.1021/ic201801e | 2011 |
| A549 | — | — | 10.1021/ic201801e | 2011 |
| A2780 | — | — | 10.1021/ic201801e | 2011 |
| A2780cisR | — | — | 10.1021/ic201801e | 2011 |
🧬 Cell Death Types (1)
Apoptosis
medium
«the appearance of a pronounced sub-G1/G0 fraction (excluded from analysis) and the tremendous decrease of the G2/M fraction (27 ± 6%) at this highest concentration suggest that apoptotic cell death is...»