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Complex #1690 — Ru(2) [1 c]

2D Structure

Structure
⬇ MOL V3000

Info

ID1690
MetalRu
Oxidation state2
Charge0
Donor atoms{"N": 1, "O": 1}
Abbreviation1 c
SMILESCc1ccc(C(C)C)cc1.Cc1ccn([O-])c(=S)c1.[Cl-]

TUCAN

C16ClNORuS/(1-14)(2-13)(3-12)(4-14)(5-8)(5-13)(6-12)(6-15)(7-9)(7-13)(8-11)(9-11)(10-12)(10-16)(11-14)(15-17)(16-17)(16-19)(17-18)

Measurements (7)

Cell lineIC₅₀ dark (µM)IC₅₀ light (µM)DOIYear
A5494.8 10.1002/chem.201903109 2019
OE1910 10.1002/chem.201903109 2019
SK-OV-315 10.1002/chem.201903109 2019
HepG219 10.1002/chem.201903109 2019
SW62633 10.1002/chem.201903109 2019
HCT-116 10.1002/chem.201903109 2019
PC-3 10.1002/chem.201903109 2019

🧬 Cell Death Types (1)

Apoptosis high
«Both compounds trigger early apoptosis»