Info
| ID | 1689 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 1 |
| Donor atoms | {"N": 4, "P": 1, "O": 1} |
| Abbreviation | 2 b |
| SMILES | C1N2CN3CN1CP(C2)C3.Cc1ccc(C(C)C)cc1.Cc1cccn([O-])c1=S |
TUCAN
C22N4OPRuS/(1-11)(2-11)(3-14)(4-12)(5-6)(5-15)(6-12)(7-8)(7-13)(8-14)(9-10)(9-14)(10-13)(11-13)(12-22)(15-26)(16-23)(16-24)(17-23)(17-25)(18-24)(18-25)(19-23)(19-28)(20-24)(20-28)(21-25)(21-28)(22-26)(22-29)(26-27)
Measurements (8)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A549 | 2.2 | — | 10.1002/chem.201903109 | 2019 |
| HCT-116 | 3.1 | — | 10.1002/chem.201903109 | 2019 |
| SK-OV-3 | 3.8 | — | 10.1002/chem.201903109 | 2019 |
| OE19 | 4 | — | 10.1002/chem.201903109 | 2019 |
| HepG2 | 7.9 | — | 10.1002/chem.201903109 | 2019 |
| MRC-5 | 9.1 | — | 10.1002/chem.201903109 | 2019 |
| SW626 | 9.4 | — | 10.1002/chem.201903109 | 2019 |
| PC-3 | 10 | — | 10.1002/chem.201903109 | 2019 |
🧬 Cell Death Types (1)
Apoptosis
high
«Both compounds trigger early apoptosis»