Info
| ID | 1688 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"N": 1, "O": 1} |
| Abbreviation | 1 b |
| SMILES | Cc1ccc(C(C)C)cc1.Cc1cccn([O-])c1=S.[Cl-] |
TUCAN
C16ClNORuS/(1-14)(2-12)(3-13)(4-14)(5-6)(5-13)(6-11)(7-9)(7-13)(8-10)(8-12)(9-11)(10-15)(11-14)(12-16)(15-17)(16-17)(16-19)(17-18)
Measurements (8)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A549 | 1.9 | — | 10.1002/chem.201903109 | 2019 |
| HCT-116 | 2.4 | — | 10.1002/chem.201903109 | 2019 |
| OE19 | 4 | — | 10.1002/chem.201903109 | 2019 |
| SK-OV-3 | 4.7 | — | 10.1002/chem.201903109 | 2019 |
| HepG2 | 8.3 | — | 10.1002/chem.201903109 | 2019 |
| MRC-5 | 8.8 | — | 10.1002/chem.201903109 | 2019 |
| SW626 | 10 | — | 10.1002/chem.201903109 | 2019 |
| PC-3 | 13 | — | 10.1002/chem.201903109 | 2019 |
🧬 Cell Death Types (1)
Apoptosis
high
«Both compounds trigger early apoptosis»