Info
| ID | 1617 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"N": 1, "O": 2} |
| Abbreviation | 4 |
| SMILES | O=C(CCc1cccnc1)OCCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F.O=C([O-])C(=O)[O-].c1ccccc1 |
TUCAN
C26H18F17NO6Ru/(1-27)(2-32)(3-28)(4-28)(5-29)(6-29)(7-19)(8-26)(9-20)(10-21)(11-25)(12-22)(13-23)(14-24)(15-27)(16-33)(17-33)(18-31)(19-20)(19-21)(20-22)(21-23)(22-24)(23-24)(25-26)(25-32)(26-30)(27-33)(27-41)(28-29)(28-36)(29-30)(30-31)(31-45)(32-45)(33-51)(34-35)(34-46)(34-47)(35-48)(35-49)(36-50)(36-51)(37-39)(37-42)(37-53)(37-54)(38-39)(38-44)(38-58)(38-64)(39-55)(39-57)(40-41)(40-43)(40-63)(40-67)(41-61)(41-62)(42-43)(42-56)(42-65)(43-66)(43-68)(44-52)(44-59)(44-60)(45-69)(51-69)
Measurements (5)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A2780 | 73 | — | 10.1021/jm501655t | 2015 |
| MDA-MB-231 | — | — | 10.1021/jm501655t | 2015 |
| HEK293 | — | — | 10.1021/jm501655t | 2015 |
| ECRF24 | — | — | 10.1021/jm501655t | 2015 |
| HUVEC | — | — | 10.1021/jm501655t | 2015 |
🧬 Cell Death Types (1)
Apoptosis
high
«For 1, only a moderate induction of apoptosis was observed in A2780 cells»