Info
| ID | 1615 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"N": 1} |
| Abbreviation | 2 |
| SMILES | O=C(CCc1cccnc1)OCCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F.[Cl-].[Cl-].c1ccccc1 |
TUCAN
C24Cl2F17NO2Ru/(1-5)(1-6)(2-3)(2-13)(3-12)(4-15)(4-18)(5-7)(6-8)(7-9)(8-9)(10-11)(10-12)(11-16)(12-14)(13-25)(14-25)(15-27)(16-26)(16-27)(17-20)(17-23)(17-32)(17-33)(18-19)(18-29)(18-31)(19-22)(19-35)(19-37)(20-21)(20-34)(20-36)(21-24)(21-38)(21-39)(22-23)(22-41)(22-44)(23-28)(23-30)(24-40)(24-42)(24-43)
Measurements (5)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A2780 | 18 | — | 10.1021/jm501655t | 2015 |
| MDA-MB-231 | — | — | 10.1021/jm501655t | 2015 |
| HEK293 | — | — | 10.1021/jm501655t | 2015 |
| ECRF24 | — | — | 10.1021/jm501655t | 2015 |
| HUVEC | — | — | 10.1021/jm501655t | 2015 |
🧬 Cell Death Types (1)
Apoptosis
high
«For 1, only a moderate induction of apoptosis was observed in A2780 cells»