Info
| ID | 1556 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 2 |
| Donor atoms | {"N": 6} |
| Abbreviation | 3 |
| SMILES | O=C(O)c1ccnc(-c2ccccn2)n1.c1ccc2nc3c4cccnc4c4ncccc4c3nc2c1.c1ccc2nc3c4cccnc4c4ncccc4c3nc2c1 |
TUCAN
C46H27N11O2Ru/(1-29)(2-43)(3-28)(4-36)(5-31)(6-35)(7-40)(8-41)(9-47)(10-37)(11-54)(12-55)(13-42)(14-30)(15-39)(16-46)(17-57)(18-56)(19-52)(20-53)(21-45)(22-34)(23-38)(24-44)(25-32)(26-33)(27-86)(28-31)(28-59)(29-36)(29-48)(30-38)(30-51)(31-37)(32-57)(32-65)(33-41)(33-56)(34-40)(34-71)(35-42)(35-52)(36-54)(37-43)(38-55)(39-44)(39-53)(40-46)(41-47)(42-49)(43-62)(44-50)(45-46)(45-64)(47-66)(48-58)(48-68)(49-60)(49-67)(50-63)(50-70)(51-61)(51-69)(52-83)(53-84)(54-74)(55-75)(56-81)(57-82)(58-67)(58-76)(59-62)(59-79)(60-68)(60-83)(61-70)(61-77)(62-76)(63-69)(63-84)(64-71)(64-77)(65-73)(65-78)(66-72)(66-81)(67-79)(68-74)(69-75)(70-80)(71-80)(72-78)(72-82)(73-85)(73-86)(79-87)(80-87)(81-87)(82-87)(83-87)(84-87)
Measurements (8)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A2780 | 2.8 | — | 10.1021/ja307288s | 2012 |
| A2780-CP70 | 4 | — | 10.1021/ja307288s | 2012 |
| MCF-7 | 4.3 | — | 10.1021/ja307288s | 2012 |
| HeLa | 10 | — | 10.1021/ja307288s | 2012 |
| U2OS | 14 | — | 10.1021/ja307288s | 2012 |
| MRC-5 | 15 | — | 10.1021/ja307288s | 2012 |
| HeLa | 16 | 5.9 | 10.1002/anie.201309576 | 2014 |
| U2OS | 30 | 14 | 10.1002/anie.201309576 | 2014 |
Source-assisted 2D generator
Builds the drawing from source ligand graphs and explicit donor metadata, then uses Metal2D only for layout. Publication output uses black bonds without arrows or colour highlighting; validated octahedral enantiomers are encoded directly with solid and hashed wedge bonds.
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The generated SVG will appear here. The legacy ligand image above stays visible for side-by-side review.