Info
| ID | 1426 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"N": 3, "S": 1, "O": 1} |
| Abbreviation | Ru3 |
| SMILES | COc1ccccc1-c1cc(-c2ccccn2)nc(-c2ccccn2)c1.CS(C)=O.[Cl-].[Cl-] |
TUCAN
C24H23N3O2RuS/(1-46)(2-31)(3-44)(4-44)(5-25)(6-29)(7-32)(8-24)(9-33)(10-30)(11-26)(12-35)(13-46)(14-46)(15-38)(16-34)(17-27)(18-44)(19-39)(20-47)(21-28)(22-47)(23-47)(24-36)(24-43)(25-29)(25-39)(26-27)(26-45)(27-30)(28-30)(28-37)(29-31)(31-40)(32-36)(32-41)(33-34)(33-38)(34-35)(35-42)(36-37)(37-45)(38-48)(39-49)(40-41)(40-49)(41-50)(42-43)(42-48)(43-50)(44-52)(45-52)(46-53)(47-53)(49-54)(50-54)(51-53)(52-54)(53-54)
Measurements (5)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| HepG2 | 7.3 | — | 10.1039/c7md00532f | 2018 |
| NCI-H460 | 9.3 | — | 10.1039/c7md00532f | 2018 |
| MGC-803 | 11 | — | 10.1039/c7md00532f | 2018 |
| HL-7702 | 17 | — | 10.1039/c7md00532f | 2018 |
| BEL-7404 | 18 | — | 10.1039/c7md00532f | 2018 |
🧬 Cell Death Types (1)
Apoptosis
high
«After treatment with Ru1 (1.3 μM) and Ru6 (3.0 μM) for 24 h, the percentage of apoptotic cells (Q2 + Q3) increased from 2.22% to 38.60% and 29.00%...»