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Complex #1378 — Ru(2) [12]

2D Structure

Structure
⬇ MOL V3000

Info

ID1378
MetalRu
Oxidation state2
Charge0
Donor atoms{"N": 2, "O": 2}
Abbreviation12
SMILESC/C(=C/C(=O)c1ccccc1)[N-]c1ccc(Cl)cc1Cl.C/C(=C/C(=O)c1ccccc1)[N-]c1ccc(Cl)cc1Cl.[C-]#[O+].[C-]#[O+]

TUCAN

C34H24Cl4N2O4Ru/(1-27)(2-25)(3-30)(4-28)(5-31)(6-33)(7-41)(8-29)(9-42)(10-25)(11-40)(12-34)(13-25)(14-36)(15-35)(16-38)(17-44)(18-43)(19-26)(20-37)(21-26)(22-26)(23-32)(24-39)(25-49)(26-50)(27-33)(27-38)(28-36)(28-47)(29-49)(29-53)(30-55)(30-56)(31-34)(31-38)(32-44)(32-48)(33-45)(34-45)(35-57)(35-58)(36-55)(37-41)(37-46)(39-42)(39-46)(40-50)(40-54)(41-43)(42-43)(44-57)(45-53)(46-54)(47-56)(47-59)(48-58)(48-60)(49-59)(50-60)(51-61)(52-62)(53-63)(54-64)(55-66)(56-65)(57-67)(58-68)(59-69)(60-69)

Measurements (3)

Cell lineIC₅₀ dark (µM)IC₅₀ light (µM)DOIYear
HCT-116 p53+/+67— 10.1016/j.ica.2019.119025 2019
ARPE-1989— 10.1016/j.ica.2019.119025 2019
MIA PaCa-292— 10.1016/j.ica.2019.119025 2019