Info
| ID | 1327 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"N": 3} |
| Abbreviation | 3a |
| SMILES | Cc1ccc(C(C)C)cc1.N#CC1=C(N)Oc2c(ccc3ccccc23)C1c1cccnc1.[Cl-].[Cl-] |
TUCAN
C29H27N3ORu/(1-35)(2-28)(3-29)(4-29)(5-50)(6-28)(7-31)(8-39)(9-51)(10-40)(11-54)(12-41)(13-32)(14-34)(15-53)(16-33)(17-29)(18-37)(19-36)(20-28)(21-30)(22-38)(23-30)(24-30)(25-42)(26-58)(27-58)(28-43)(29-50)(30-50)(31-40)(31-48)(32-35)(32-45)(33-34)(33-41)(34-39)(35-46)(36-37)(36-43)(37-44)(38-42)(38-44)(39-45)(40-53)(41-47)(42-43)(44-50)(45-47)(46-51)(46-55)(47-55)(48-51)(48-54)(49-51)(49-52)(49-56)(52-57)(53-59)(54-59)(55-60)(56-58)(56-60)(59-61)(60-61)
Measurements (13)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| MCF-7/Topo | 0.011 | — | 10.1016/j.jinorgbio.2018.03.01... | 2018 |
| KB-V1/Vbl | 0.013 | — | 10.1016/j.jinorgbio.2018.03.01... | 2018 |
| PANC-1 | 0.013 | — | 10.1016/j.jinorgbio.2018.03.01... | 2018 |
| LoVo | 0.014 | — | 10.1016/j.cbi.2024.111180 | 2024 |
| DU-145 | 0.018 | — | 10.1016/j.cbi.2024.111180 | 2024 |
| 518A2 | 0.038 | — | 10.1016/j.jinorgbio.2018.03.01... | 2018 |
| DLD-1 | 0.039 | — | 10.1016/j.jinorgbio.2018.03.01... | 2018 |
| HT-29 | 0.054 | — | 10.1016/j.jinorgbio.2018.03.01... | 2018 |
| HCT-116 | 0.061 | — | 10.1016/j.jinorgbio.2018.03.01... | 2018 |
| U-87 MG | 0.28 | — | 10.1016/j.jinorgbio.2018.03.01... | 2018 |
| MDA-MB-231 | 8.1 | — | 10.1016/j.cbi.2024.111180 | 2024 |
| 518A2 | — | — | 10.1016/j.jinorgbio.2018.03.01... | 2018 |
| HDFa | — | — | 10.1016/j.jinorgbio.2018.03.01... | 2018 |