Info
| ID | 1320 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 1 |
| Donor atoms | {"N": 2, "P": 2} |
| Abbreviation | 2pA |
| SMILES | COC(=O)C(C)NC(=O)c1ccc(P(c2ccccc2)c2ccccc2)cc1.COC(=O)C(C)NC(=O)c1ccc(P(c2ccccc2)c2ccccc2)cc1.Cc1ccc(C(C)C)cc1.[Cl-] |
TUCAN
C56H58N2O6P2Ru/(1-59)(2-59)(3-80)(4-59)(5-65)(6-103)(7-66)(8-64)(9-81)(10-60)(11-68)(12-67)(13-60)(14-70)(15-72)(16-71)(17-103)(18-74)(19-62)(20-69)(21-76)(22-75)(23-78)(24-77)(25-82)(26-62)(27-61)(28-61)(29-100)(30-61)(31-88)(32-62)(33-89)(34-60)(35-83)(36-73)(37-63)(38-63)(39-84)(40-101)(41-92)(42-63)(43-86)(44-90)(45-91)(46-93)(47-79)(48-102)(49-85)(50-103)(51-87)(52-95)(53-104)(54-104)(55-94)(56-104)(57-115)(58-116)(59-100)(60-98)(61-100)(62-101)(63-102)(64-80)(64-98)(65-73)(65-109)(66-68)(66-70)(67-68)(67-71)(69-76)(69-78)(70-110)(71-110)(72-92)(72-109)(73-97)(74-93)(74-113)(75-78)(75-82)(76-111)(77-79)(77-88)(79-84)(80-96)(81-83)(81-98)(82-111)(83-96)(84-89)(85-86)(85-87)(86-90)(87-94)(88-112)(89-112)(90-114)(91-95)(91-113)(92-97)(93-99)(94-114)(95-99)(96-100)(97-105)(99-106)(101-107)(101-115)(102-108)(102-116)(103-121)(104-122)(105-115)(105-118)(106-116)(106-119)(107-117)(107-121)(108-120)(108-122)(109-123)(110-123)(111-123)(112-124)(113-124)(114-124)(121-125)(122-125)(123-125)(124-125)
Measurements (1)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| HeLa | 15 | — | 10.1016/j.bioorg.2019.03.048 | 2019 |
🧬 Cell Death Types (1)
Autophagy
high
«Further investigation determined autophagy as the mode of cell death.»