Info
| ID | 1319 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 1 |
| Donor atoms | {"N": 2, "P": 2} |
| Abbreviation | 2pG |
| SMILES | COC(=O)CNC(=O)c1ccc(P(c2ccccc2)c2ccccc2)cc1.COC(=O)CNC(=O)c1ccc(P(c2ccccc2)c2ccccc2)cc1.Cc1ccc(C(C)C)cc1.[Cl-] |
TUCAN
C54H54N2O6P2Ru/(1-55)(2-55)(3-66)(4-55)(5-72)(6-97)(7-59)(8-58)(9-67)(10-56)(11-69)(12-65)(13-56)(14-60)(15-76)(16-61)(17-62)(18-68)(19-75)(20-97)(21-71)(22-77)(23-63)(24-80)(25-74)(26-85)(27-97)(28-57)(29-57)(30-94)(31-57)(32-64)(33-98)(34-73)(35-56)(36-70)(37-79)(38-95)(39-95)(40-81)(41-98)(42-82)(43-78)(44-84)(45-96)(46-96)(47-98)(48-87)(49-86)(50-88)(51-83)(52-89)(53-109)(54-110)(55-94)(56-91)(57-94)(58-66)(58-91)(59-60)(59-69)(60-103)(61-65)(61-103)(62-72)(62-92)(63-68)(63-104)(64-71)(64-104)(65-69)(66-90)(67-70)(67-91)(68-75)(70-90)(71-75)(72-106)(73-77)(73-105)(74-76)(74-92)(76-106)(77-85)(78-81)(78-105)(79-80)(79-93)(80-107)(81-85)(82-83)(82-107)(83-93)(84-88)(84-108)(86-88)(86-89)(87-89)(87-108)(90-94)(92-99)(93-100)(95-101)(95-109)(96-102)(96-110)(97-115)(98-116)(99-109)(99-112)(100-110)(100-113)(101-111)(101-115)(102-114)(102-116)(103-117)(104-117)(105-118)(106-117)(107-118)(108-118)(115-119)(116-119)(117-119)(118-119)
Measurements (1)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| HeLa | 30 | — | 10.1016/j.bioorg.2019.03.048 | 2019 |
🧬 Cell Death Types (1)
Autophagy
high
«Further investigation determined autophagy as the mode of cell death.»