Info
| ID | 1223 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"N": 3, "S": 1, "O": 1, "P": 2} |
| Abbreviation | 2 |
| SMILES | CN/C([S-])=N/N=C(\C)c1[c-]c2ccccc2oc1=O.[C-]#[O+].c1ccc(P(c2ccccc2)c2ccccc2)cc1.c1ccc(P(c2ccccc2)c2ccccc2)cc1 |
TUCAN
C50H41N3O3P2RuS/(1-44)(2-45)(3-46)(4-47)(5-48)(6-49)(7-51)(8-50)(9-55)(10-42)(11-42)(12-53)(13-56)(14-60)(15-52)(16-54)(17-61)(18-57)(19-58)(20-62)(21-64)(22-59)(23-80)(24-80)(25-80)(26-63)(27-66)(28-65)(29-67)(30-69)(31-70)(32-68)(33-73)(34-71)(35-72)(36-75)(37-76)(38-77)(39-42)(40-74)(41-92)(42-81)(43-78)(43-79)(44-45)(44-47)(45-46)(46-48)(47-85)(48-85)(49-50)(49-86)(50-55)(51-53)(51-86)(52-56)(52-87)(53-55)(54-60)(54-87)(56-59)(57-61)(57-88)(58-64)(58-88)(59-60)(61-63)(62-66)(62-89)(63-64)(65-68)(65-89)(66-67)(67-68)(69-71)(69-90)(70-72)(70-90)(71-73)(72-73)(74-75)(74-83)(75-76)(76-77)(77-78)(78-83)(79-81)(79-84)(80-92)(81-93)(82-96)(83-97)(84-95)(84-97)(85-98)(86-98)(87-98)(88-99)(89-99)(90-99)(91-92)(91-94)(91-100)(93-94)(93-101)(94-101)(97-101)(98-101)(99-101)
Measurements (3)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A549 | 2.8 | — | 10.1039/c7nj02877f | 2018 |
| MCF-7 | 2.9 | — | 10.1039/c7nj02877f | 2018 |
| HaCaT | — | — | 10.1039/c7nj02877f | 2018 |
🧬 Cell Death Types (1)
Apoptosis
high
«Based on the results obtained with this assay, we conclude that these compounds induced cell death by apoptosis.»