Info
| ID | 1221 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"O": 1, "P": 3} |
| Abbreviation | [RuHClCO(PPh3)3] |
| SMILES | [C-]#[O+].[Cl-].[H-].c1ccc(P(c2ccccc2)c2ccccc2)cc1.c1ccc(P(c2ccccc2)c2ccccc2)cc1.c1ccc(P(c2ccccc2)c2ccccc2)cc1 |
TUCAN
C55H45OP3Ru/(1-47)(2-51)(3-53)(4-55)(5-52)(6-54)(7-59)(8-46)(9-48)(10-49)(11-61)(12-57)(13-50)(14-56)(15-62)(16-60)(17-64)(18-66)(19-58)(20-63)(21-68)(22-65)(23-67)(24-70)(25-73)(26-74)(27-75)(28-76)(29-69)(30-71)(31-77)(32-79)(33-72)(34-78)(35-80)(36-81)(37-83)(38-85)(39-84)(40-82)(41-88)(42-86)(43-87)(44-90)(45-89)(46-47)(46-92)(47-53)(48-51)(48-92)(49-52)(49-93)(50-54)(50-93)(51-53)(52-55)(54-55)(56-59)(56-94)(57-59)(57-61)(58-61)(58-94)(60-62)(60-64)(62-63)(63-95)(64-65)(65-95)(66-68)(66-73)(67-68)(67-96)(69-73)(69-96)(70-75)(70-76)(71-75)(71-97)(72-76)(72-97)(74-77)(74-79)(77-78)(78-98)(79-80)(80-98)(81-83)(81-85)(82-84)(82-85)(83-99)(84-99)(86-88)(86-100)(87-90)(87-100)(88-89)(89-90)(91-101)(92-102)(93-102)(94-102)(95-103)(96-103)(97-103)(98-104)(99-104)(100-104)(102-105)(103-105)(104-105)
Measurements (6)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A549 | 16 | — | 10.1039/c7nj02877f | 2018 |
| A549 | 16 | — | 10.1016/j.jorganchem.2018.04.0... | 2018 |
| MCF-7 | 20 | — | 10.1039/c7nj02877f | 2018 |
| MCF-7 | 20 | — | 10.1016/j.jorganchem.2018.04.0... | 2018 |
| HaCaT | — | — | 10.1039/c7nj02877f | 2018 |
| HaCaT | — | — | 10.1016/j.jorganchem.2018.04.0... | 2018 |
🧬 Cell Death Types (1)
Apoptosis
high
«Based on the results obtained with this assay, we conclude that these compounds induced cell death by apoptosis.»
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