Info
| ID | 119 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 1 |
| Donor atoms | {"O": 1, "P": 2} |
| Abbreviation | 4 |
| SMILES | OCCCCc1ccccc1.[Cl-].c1ccc(P(c2ccccc2)c2ccc3ccccc3c2-c2c(P(c3ccccc3)c3ccccc3)ccc3ccccc23)cc1 |
TUCAN
C54H46OP2Ru/(1-51)(2-49)(3-58)(4-47)(5-70)(6-62)(7-57)(8-84)(9-54)(10-56)(11-66)(12-60)(13-63)(14-68)(15-52)(16-50)(17-71)(18-72)(19-64)(20-48)(21-73)(22-53)(23-65)(24-55)(25-67)(26-77)(27-69)(28-74)(29-78)(30-59)(31-82)(32-83)(33-79)(34-61)(35-84)(36-85)(37-86)(38-76)(39-75)(40-86)(41-94)(42-94)(43-80)(44-81)(45-85)(46-101)(47-50)(47-51)(48-49)(48-62)(49-58)(50-56)(51-89)(52-53)(52-70)(53-59)(54-55)(54-90)(55-96)(56-90)(57-80)(57-91)(58-95)(59-93)(60-61)(60-93)(61-98)(62-63)(63-95)(64-66)(64-97)(65-68)(65-97)(66-67)(67-68)(69-71)(69-99)(70-92)(71-82)(72-74)(72-82)(73-78)(73-83)(74-99)(75-80)(75-81)(76-81)(76-91)(77-79)(77-83)(78-100)(79-100)(84-85)(84-91)(85-86)(86-94)(87-88)(87-89)(87-96)(88-92)(88-98)(89-90)(92-93)(94-101)(95-102)(96-102)(97-102)(98-103)(99-103)(100-103)(101-104)(102-104)(103-104)
Measurements (2)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| HeLa | 21 | — | 10.1021/acs.inorgchem.7b01959 | 2017 |
| A549 | 31 | — | 10.1021/acs.inorgchem.7b01959 | 2017 |
🧬 Cell Death Types (1)
Apoptosis
high
«The results suggested that cell death caused by the complexes was induced mainly through apoptosis.»