Info
| ID | 118 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 1 |
| Donor atoms | {"O": 1, "P": 2} |
| Abbreviation | 3 |
| SMILES | OCCCc1ccccc1.[Cl-].c1ccc(P(c2ccccc2)c2ccc3ccccc3c2-c2c(P(c3ccccc3)c3ccccc3)ccc3ccccc23)cc1 |
TUCAN
C53H44OP2Ru/(1-45)(2-46)(3-57)(4-49)(5-55)(6-53)(7-80)(8-52)(9-68)(10-60)(11-58)(12-61)(13-59)(14-48)(15-50)(16-47)(17-63)(18-62)(19-66)(20-64)(21-65)(22-51)(23-67)(24-69)(25-71)(26-73)(27-70)(28-76)(29-72)(30-56)(31-75)(32-79)(33-77)(34-78)(35-74)(36-82)(37-82)(38-83)(39-83)(40-91)(41-91)(42-54)(43-81)(44-98)(45-48)(45-86)(46-47)(46-57)(47-55)(48-51)(49-50)(49-88)(50-56)(51-52)(52-87)(53-54)(53-80)(54-89)(55-59)(56-68)(57-93)(58-61)(58-87)(59-93)(60-62)(60-64)(61-92)(62-94)(63-64)(63-66)(65-67)(65-73)(66-94)(67-95)(68-90)(69-78)(69-97)(70-71)(70-95)(71-73)(72-76)(72-96)(74-80)(74-81)(75-76)(75-79)(77-79)(77-96)(78-90)(81-89)(82-83)(82-89)(83-91)(84-85)(84-86)(84-92)(85-88)(85-97)(86-87)(88-90)(91-98)(92-99)(93-99)(94-99)(95-100)(96-100)(97-100)(98-101)(99-101)(100-101)
Measurements (2)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| HeLa | 24 | — | 10.1021/acs.inorgchem.7b01959 | 2017 |
| A549 | 35 | — | 10.1021/acs.inorgchem.7b01959 | 2017 |
🧬 Cell Death Types (1)
Apoptosis
high
«The results suggested that cell death caused by the complexes was induced mainly through apoptosis.»