Info
| ID | 1174 |
| Metal | Ru |
| Oxidation state | 3 |
| Charge | 0 |
| Donor atoms | {"O": 1, "N": 2, "P": 2} |
| Abbreviation | 1 |
| SMILES | [Cl-].[Cl-].[O-]/C(=N\N=C/c1c(O)ccc2ccccc12)c1ccccc1.c1ccc(P(c2ccccc2)c2ccccc2)cc1.c1ccc(P(c2ccccc2)c2ccccc2)cc1 |
TUCAN
C54H43N2O2P2Ru/(1-46)(2-44)(3-53)(4-47)(5-55)(6-50)(7-45)(8-48)(9-49)(10-51)(11-82)(12-58)(13-59)(14-83)(15-84)(16-52)(17-54)(18-57)(19-56)(20-63)(21-62)(22-66)(23-64)(24-67)(25-60)(26-89)(27-61)(28-74)(29-65)(30-71)(31-70)(32-77)(33-78)(34-79)(35-76)(36-80)(37-73)(38-69)(39-68)(40-75)(41-81)(42-72)(43-101)(44-46)(44-92)(45-47)(45-92)(46-53)(47-53)(48-50)(48-93)(49-51)(49-93)(50-55)(51-55)(52-54)(52-60)(54-94)(56-57)(56-94)(57-60)(58-59)(58-90)(59-85)(61-63)(61-66)(62-63)(62-95)(64-66)(64-95)(65-67)(65-96)(67-74)(68-69)(68-73)(69-72)(70-71)(70-96)(71-74)(72-75)(73-87)(75-87)(76-79)(76-80)(77-79)(77-97)(78-80)(78-97)(81-82)(81-88)(82-83)(83-84)(84-85)(85-88)(86-88)(86-89)(86-90)(87-91)(89-98)(90-101)(91-99)(91-100)(92-102)(93-102)(94-102)(95-103)(96-103)(97-103)(98-99)(98-104)(99-104)(101-104)(102-104)(103-104)
Measurements (1)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A549 | 18 | — | 10.1039/c5dt03849a | 2016 |
🧬 Cell Death Types (1)
Apoptosis
high
«The chromatin condensation, nuclear shrinkage, and plasma membrane blebbing were observed using fluorescence microscope those are the clear indication of apoptic cell death pattern. (PI staining secti...»