Info
| ID | 1149 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 1 |
| Donor atoms | {"N": 2} |
| Abbreviation | (8) |
| SMILES | C/C(=N\c1c(C(C)C)cccc1C(C)C)[n+]1[c-]n(C(C)C)cc1.Cc1ccc(C(C)C)cc1.[Cl-] |
TUCAN
C30ClN3Ru/(1-18)(2-27)(3-19)(4-18)(5-19)(6-24)(7-22)(8-24)(9-27)(10-30)(11-13)(11-20)(12-14)(12-22)(13-16)(14-21)(15-17)(15-21)(16-23)(17-22)(18-21)(19-20)(20-28)(23-24)(23-28)(25-26)(25-32)(26-33)(27-33)(28-31)(29-32)(29-33)(30-31)(30-32)
Measurements (1)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A549 | 25 | — | 10.1002/asia.201801058 | 2018 |
🧬 Cell Death Types (2)
Apoptosis
high
«These results suggested that complex 9 can induce A549 cell death through a high incidence of apoptosis.»
Lysosomal Cell Death
medium
«Interestingly, lysosomal damage was detected in A549 cancer cells by confocal microscopy, suggesting that these complexes may mediate cell death through lysosomal damage.»
Source-assisted 2D generator
Builds the drawing from source ligand graphs and explicit donor metadata, then uses Metal2D only for layout. Publication output uses black bonds without arrows or colour highlighting; validated octahedral enantiomers are encoded directly with solid and hashed wedge bonds.
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