Info
| ID | 1146 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 1 |
| Donor atoms | {"N": 2} |
| Abbreviation | (5) |
| SMILES | CC(C)n1[c-][n+](/C(=N/c2ccccc2)c2ccccc2)cc1.Cc1ccc(C(C)C)cc1.[Cl-] |
TUCAN
C29ClN3Ru/(1-27)(2-21)(3-21)(4-23)(5-27)(6-8)(6-20)(7-19)(7-20)(8-23)(9-11)(9-13)(10-17)(10-26)(11-12)(12-22)(13-16)(14-17)(14-18)(15-18)(15-26)(16-22)(19-23)(20-21)(22-29)(24-25)(24-31)(25-32)(26-30)(27-31)(28-31)(28-32)(29-30)(29-32)
Measurements (1)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A549 | 52 | — | 10.1002/asia.201801058 | 2018 |
🧬 Cell Death Types (2)
Apoptosis
high
«These results suggested that complex 9 can induce A549 cell death through a high incidence of apoptosis.»
Lysosomal Cell Death
medium
«Interestingly, lysosomal damage was detected in A549 cancer cells by confocal microscopy, suggesting that these complexes may mediate cell death through lysosomal damage.»