Info
| ID | 1141 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 1 |
| Donor atoms | {"N": 2} |
| Abbreviation | 9 |
| SMILES | Cc1c(C)c(C)c(C)c(C)c1C.Clc1cccc(/N=C/c2ccc3ccccc3n2)c1.[Cl-] |
TUCAN
C28H29ClN2Ru/(1-37)(2-40)(3-30)(4-30)(5-30)(6-31)(7-31)(8-31)(9-32)(10-39)(11-41)(12-44)(13-45)(14-53)(15-43)(16-36)(17-42)(18-38)(19-32)(20-32)(21-33)(22-33)(23-33)(24-34)(25-34)(26-34)(27-35)(28-35)(29-35)(30-46)(31-47)(32-48)(33-49)(34-50)(35-51)(36-37)(36-56)(37-40)(38-45)(38-54)(39-56)(39-57)(40-57)(41-43)(41-45)(42-44)(42-52)(43-52)(44-55)(46-47)(46-48)(47-49)(48-50)(49-51)(50-51)(52-54)(53-55)(53-59)(54-58)(55-58)(56-59)(57-60)(58-61)(59-61)
Measurements (7)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| AGS | 1.9 | — | 10.1021/acs.molpharmaceut.6b00... | 2016 |
| KATO III | 2.2 | — | 10.1021/acs.molpharmaceut.6b00... | 2016 |
| HCT-116 | 3 | — | 10.1021/acs.molpharmaceut.6b00... | 2016 |
| MCF-7 | 6.5 | — | 10.1021/jm500455p | 2014 |
| A2780 | 7.6 | — | 10.1021/jm500455p | 2014 |
| A2780cisR | 9.8 | — | 10.1021/jm500455p | 2014 |
| SW480 | 16 | — | 10.1021/acs.molpharmaceut.6b00... | 2016 |
Source-assisted 2D generator
Builds the drawing from source ligand graphs and explicit donor metadata, then uses Metal2D only for layout. Publication output uses black bonds without arrows or colour highlighting; validated octahedral enantiomers are encoded directly with solid and hashed wedge bonds.
Loading source metadata…
The generated SVG will appear here. The legacy ligand image above stays visible for side-by-side review.