Info
| ID | 102 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"O": 1, "N": 2} |
| Abbreviation | 5 |
| SMILES | Cc1ccc(C(C)C)cc1.[Cl-].[O-]/C(=N\N=C/c1c2ccccc2cc2ccccc12)c1ccc(Cl)cc1 |
TUCAN
C32H28ClN2ORu/(1-45)(2-39)(3-36)(4-30)(5-30)(6-35)(7-32)(8-38)(9-42)(10-43)(11-46)(12-41)(13-40)(14-58)(15-34)(16-33)(17-44)(18-47)(19-30)(20-29)(21-29)(22-31)(23-48)(24-57)(25-29)(26-31)(27-37)(28-31)(29-53)(30-57)(31-57)(32-43)(32-60)(33-52)(33-55)(34-38)(34-49)(35-36)(35-53)(36-54)(37-48)(37-54)(38-45)(39-45)(39-52)(40-44)(40-46)(41-46)(41-55)(42-47)(42-60)(43-56)(44-50)(47-56)(48-53)(49-51)(49-52)(50-51)(50-55)(51-58)(54-57)(56-59)(58-62)(59-61)(59-63)(60-64)(61-62)(61-65)(62-65)
Measurements (4)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| MDA-MB-231 | 18 | — | 10.1039/c6qi00197a | 2016 |
| HepG2 | 23 | — | 10.1039/c6qi00197a | 2016 |
| HeLa | 23 | — | 10.1039/c6qi00197a | 2016 |
| NIH-3T3 | 2.3e+02 | — | 10.1039/c6qi00197a | 2016 |
🧬 Cell Death Types (1)
Apoptosis
high
«Furthermore, the results of AO–EB, Hoechst 33258 and flow cytometry analyses reveal that these complexes induce cell death only through apoptosis.»