Info
| ID | 101 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"O": 1, "N": 2} |
| Abbreviation | 4 |
| SMILES | Cc1ccc(C(C)C)cc1.[Cl-].[O-]/C(=N\N=C/c1c2ccccc2cc2ccccc12)c1ccccc1 |
TUCAN
C32H29N2ORu/(1-35)(2-43)(3-44)(4-31)(5-38)(6-39)(7-31)(8-41)(9-36)(10-49)(11-34)(12-46)(13-37)(14-42)(15-45)(16-60)(17-33)(18-47)(19-48)(20-31)(21-50)(22-30)(23-32)(24-32)(25-30)(26-30)(27-32)(28-59)(29-40)(30-53)(31-59)(32-59)(33-35)(33-37)(34-36)(34-49)(35-52)(36-41)(37-43)(38-39)(38-53)(39-54)(40-50)(40-54)(41-57)(42-56)(42-58)(43-56)(44-48)(44-55)(45-47)(45-48)(46-49)(46-57)(47-58)(50-53)(51-52)(51-55)(51-60)(52-56)(54-59)(55-58)(57-61)(60-62)(61-63)(61-64)(62-63)(62-65)(63-65)
Measurements (4)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| MDA-MB-231 | 10 | — | 10.1039/c6qi00197a | 2016 |
| HepG2 | 12 | — | 10.1039/c6qi00197a | 2016 |
| HeLa | 19 | — | 10.1039/c6qi00197a | 2016 |
| NIH-3T3 | 2.4e+02 | — | 10.1039/c6qi00197a | 2016 |
🧬 Cell Death Types (1)
Apoptosis
high
«Furthermore, the results of AO–EB, Hoechst 33258 and flow cytometry analyses reveal that these complexes induce cell death only through apoptosis.»