Info
| ID | 1 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 1 |
| Donor atoms | {"N": 5, "P": 1} |
| Abbreviation | 5 |
| SMILES | N#Cc1ccc(C(c2ccc(C#N)cc2)n2cncn2)cc1.N#Cc1ccc(C(c2ccc(C#N)cc2)n2cncn2)cc1.[Cl-].c1ccc(P(c2ccccc2)c2ccccc2)cc1 |
TUCAN
C52H37N10PRu/(1-43)(2-39)(3-46)(4-38)(5-45)(6-40)(7-41)(8-42)(9-44)(10-47)(11-52)(12-48)(13-55)(14-81)(15-50)(16-82)(17-56)(18-49)(19-51)(20-65)(21-53)(22-60)(23-63)(24-54)(25-58)(26-57)(27-59)(28-64)(29-61)(30-83)(31-84)(32-86)(33-66)(34-62)(35-68)(36-67)(37-85)(38-42)(38-43)(39-46)(39-72)(40-42)(40-44)(41-50)(41-51)(43-87)(44-87)(45-47)(45-72)(46-69)(47-69)(48-52)(48-70)(49-50)(49-53)(51-88)(52-73)(53-88)(54-58)(54-89)(55-60)(55-70)(56-63)(56-71)(57-61)(57-89)(58-65)(59-64)(59-71)(60-73)(61-65)(62-66)(62-74)(63-75)(64-75)(66-76)(67-68)(67-76)(68-74)(69-77)(70-78)(71-79)(72-81)(73-81)(74-80)(75-82)(76-82)(77-90)(78-91)(79-92)(80-93)(81-94)(82-95)(83-96)(83-98)(84-94)(84-96)(85-95)(85-97)(86-97)(86-99)(87-100)(88-100)(89-100)(94-98)(95-99)(96-101)(97-101)(98-101)(99-101)(100-101)
Measurements (1)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| MCF-7 | 36 | — | 10.1021/jm301103y | 2012 |
🧬 Cell Death Types (1)
Autophagy
medium
«the resultant cancer cell death likely involves 5·Let-induced autophagy.»