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Complex #600 — Ru(2) [2d]

2D Structure

Structure
⬇ MOL V3000

Info

ID600
MetalRu
Oxidation state2
Charge1
Donor atoms{"N": 3}
Abbreviation2d
SMILESCc1cc(O)n(C(N)=S)n1.Cc1ccc(C(C)C)cc1.[Cl-]

TUCAN

C15H21N3ORuS/(1-22)(2-25)(3-22)(4-26)(5-22)(6-23)(7-23)(8-27)(9-23)(10-24)(11-24)(12-28)(13-25)(14-29)(15-33)(16-25)(17-30)(18-24)(19-37)(20-37)(21-40)(22-33)(23-33)(24-34)(25-31)(26-27)(26-32)(27-31)(28-29)(28-31)(29-32)(30-34)(30-35)(32-33)(34-39)(35-38)(35-40)(36-37)(36-38)(36-41)(38-39)(39-42)(40-42)

Measurements (33)

Cell lineIC₅₀ dark (µM)IC₅₀ light (µM)DOIYear
WM1158— 10.1039/c9ra08736b 2019
WM1158— 10.3390/molecules28093969 2023
HEC-1-A68— 10.3390/molecules28093969 2023
Ishikawa1e+02— 10.3390/molecules28093969 2023
LoVo1.1e+02— 10.3390/molecules28093969 2023
HeLa1.1e+02— 10.3390/molecules28093969 2023
HEC-1-A1.3e+02— 10.3390/molecules28093969 2023
A5491.5e+02— 10.3390/molecules28093969 2023
Caco-21.6e+02— 10.3390/molecules28093969 2023
HT-291.7e+02— 10.3390/molecules28093969 2023
HT-291.9e+02— 10.3390/molecules28093969 2023
HCC381.9e+02— 10.3390/molecules28093969 2023
NALM64.9e+02— 10.1039/c9ra08736b 2019
HL605.9e+02— 10.1039/c9ra08736b 2019
COLO-205—— 10.3390/molecules28093969 2023
SW620—— 10.3390/molecules28093969 2023
LoVo—— 10.3390/molecules28093969 2023
Caco-2—— 10.3390/molecules28093969 2023
Hep3B—— 10.3390/molecules28093969 2023
A549—— 10.3390/molecules28093969 2023
HCC38—— 10.3390/molecules28093969 2023
MCF-7—— 10.3390/molecules28093969 2023
NALM6—— 10.3390/molecules28093969 2023
HL60—— 10.3390/molecules28093969 2023
COLO-205—— 10.3390/molecules28093969 2023
SW620—— 10.3390/molecules28093969 2023
Hep3B—— 10.3390/molecules28093969 2023
Ishikawa—— 10.3390/molecules28093969 2023
HeLa—— 10.3390/molecules28093969 2023
MCF-7—— 10.3390/molecules28093969 2023
WM115—— 10.3390/molecules28093969 2023
NALM6—— 10.3390/molecules28093969 2023
HL60—— 10.3390/molecules28093969 2023

🧬 Cell Death Types (1)

Apoptosis high
«Microscopic analysis showed that ruthenium derivatives induce apoptosis in cancer cells.»