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Complex #598 — Ru(2) [2a]

2D Structure

Structure
⬇ MOL V3000

Info

ID598
MetalRu
Oxidation state2
Charge1
Donor atoms{"N": 3}
Abbreviation2a
SMILESCc1cc(C)n(C(N)=S)n1.Cc1ccc(C(C)C)cc1.[Cl-]

TUCAN

C16ClN3RuS/(1-12)(2-12)(3-13)(4-15)(5-14)(6-14)(6-15)(7-8)(7-13)(8-11)(9-10)(9-11)(10-13)(11-12)(14-19)(15-18)(16-17)(16-19)(16-20)(18-19)

Measurements (33)

Cell lineIC₅₀ dark (µM)IC₅₀ light (µM)DOIYear
NALM646— 10.3390/molecules28093969 2023
NALM652— 10.1039/c9ra08736b 2019
NALM652— 10.3390/molecules28093969 2023
Hep3B55— 10.3390/molecules28093969 2023
COLO-20560— 10.3390/molecules28093969 2023
WM11560— 10.3390/molecules28093969 2023
WM11560— 10.1039/c9ra08736b 2019
HEC-1-A62— 10.3390/molecules28093969 2023
SW62064— 10.3390/molecules28093969 2023
WM11564— 10.3390/molecules28093969 2023
HEC-1-A77— 10.3390/molecules28093969 2023
HL6080— 10.3390/molecules28093969 2023
HCC3884— 10.3390/molecules28093969 2023
HL6089— 10.1039/c9ra08736b 2019
HL6089— 10.3390/molecules28093969 2023
Ishikawa91— 10.3390/molecules28093969 2023
HeLa99— 10.3390/molecules28093969 2023
Caco-21.1e+02— 10.3390/molecules28093969 2023
COLO-2051.1e+02— 10.3390/molecules28093969 2023
HT-291.1e+02— 10.3390/molecules28093969 2023
SW6201.2e+02— 10.3390/molecules28093969 2023
A5491.2e+02— 10.3390/molecules28093969 2023
HT-291.2e+02— 10.3390/molecules28093969 2023
LoVo1.3e+02— 10.3390/molecules28093969 2023
LoVo—— 10.3390/molecules28093969 2023
Caco-2—— 10.3390/molecules28093969 2023
Hep3B—— 10.3390/molecules28093969 2023
HeLa—— 10.3390/molecules28093969 2023
MCF-7—— 10.3390/molecules28093969 2023
Ishikawa—— 10.3390/molecules28093969 2023
A549—— 10.3390/molecules28093969 2023
HCC38—— 10.3390/molecules28093969 2023
MCF-7—— 10.3390/molecules28093969 2023

🧬 Cell Death Types (1)

Apoptosis high
«Microscopic analysis showed that ruthenium derivatives induce apoptosis in cancer cells.»