home← all complexes Ir builderC^N familiesD-MPNN

Complex #598 — Ru(2) [2a]

2D Structure

Structure
⬇ MOL V3000

Info

ID598
MetalRu
Oxidation state2
Charge1
Donor atoms{"N": 3}
Abbreviation2a
SMILESCc1cc(C)n(C(N)=S)n1.Cc1ccc(C(C)C)cc1.[Cl-]

TUCAN

C16ClN3RuS/(1-12)(2-12)(3-13)(4-15)(5-14)(6-14)(6-15)(7-8)(7-13)(8-11)(9-10)(9-11)(10-13)(11-12)(14-19)(15-18)(16-17)(16-19)(16-20)(18-19)

Measurements (33)

Cell lineIC₅₀ dark (µM)IC₅₀ light (µM)DOIYear
NALM646— 10.3390/molecules28093969 2023
NALM652— 10.1039/c9ra08736b 2019
NALM652— 10.3390/molecules28093969 2023
Hep3B55— 10.3390/molecules28093969 2023
COLO-20560— 10.3390/molecules28093969 2023
WM11560— 10.3390/molecules28093969 2023
WM11560— 10.1039/c9ra08736b 2019
HEC-1-A62— 10.3390/molecules28093969 2023
SW62064— 10.3390/molecules28093969 2023
WM11564— 10.3390/molecules28093969 2023
HEC-1-A77— 10.3390/molecules28093969 2023
HL6080— 10.3390/molecules28093969 2023
HCC3884— 10.3390/molecules28093969 2023
HL6089— 10.1039/c9ra08736b 2019
HL6089— 10.3390/molecules28093969 2023
Ishikawa91— 10.3390/molecules28093969 2023
HeLa99— 10.3390/molecules28093969 2023
Caco-21.1e+02— 10.3390/molecules28093969 2023
COLO-2051.1e+02— 10.3390/molecules28093969 2023
HT-291.1e+02— 10.3390/molecules28093969 2023
SW6201.2e+02— 10.3390/molecules28093969 2023
A5491.2e+02— 10.3390/molecules28093969 2023
HT-291.2e+02— 10.3390/molecules28093969 2023
LoVo1.3e+02— 10.3390/molecules28093969 2023
LoVo—— 10.3390/molecules28093969 2023
Caco-2—— 10.3390/molecules28093969 2023
Hep3B—— 10.3390/molecules28093969 2023
HeLa—— 10.3390/molecules28093969 2023
MCF-7—— 10.3390/molecules28093969 2023
Ishikawa—— 10.3390/molecules28093969 2023
A549—— 10.3390/molecules28093969 2023
HCC38—— 10.3390/molecules28093969 2023
MCF-7—— 10.3390/molecules28093969 2023

🧬 Cell Death Types (1)

Apoptosis high
«Microscopic analysis showed that ruthenium derivatives induce apoptosis in cancer cells.»

Source-assisted 2D generator

Builds the drawing from source ligand graphs and explicit donor metadata, then uses Metal2D only for layout. Publication output uses black bonds without arrows or colour highlighting; validated octahedral enantiomers are encoded directly with solid and hashed wedge bonds.

experimental validation surface
Loading source metadata…
The generated SVG will appear here. The legacy ligand image above stays visible for side-by-side review.