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Complex #597 — Ru(2) [2b]

2D Structure

Structure
⬇ MOL V3000

Info

ID597
MetalRu
Oxidation state2
Charge1
Donor atoms{"N": 3}
Abbreviation2b
SMILESCCc1cc(CC)n(C(N)=S)n1.Cc1ccc(C(C)C)cc1.[Cl-]

TUCAN

C18ClN3RuS/(1-9)(2-14)(3-14)(4-15)(5-10)(6-7)(6-15)(7-13)(8-12)(8-13)(9-16)(10-17)(11-16)(11-17)(12-15)(13-14)(16-20)(17-21)(18-19)(18-21)(18-22)(20-21)

Measurements (33)

Cell lineIC₅₀ dark (µM)IC₅₀ light (µM)DOIYear
NALM618— 10.3390/molecules28093969 2023
HEC-1-A36— 10.3390/molecules28093969 2023
NALM640— 10.3390/molecules28093969 2023
NALM640— 10.1039/c9ra08736b 2019
HEC-1-A40— 10.3390/molecules28093969 2023
Ishikawa51— 10.3390/molecules28093969 2023
WM11552— 10.3390/molecules28093969 2023
HL6053— 10.3390/molecules28093969 2023
WM11555— 10.1039/c9ra08736b 2019
WM11555— 10.3390/molecules28093969 2023
LoVo60— 10.3390/molecules28093969 2023
Hep3B62— 10.3390/molecules28093969 2023
HCC3864— 10.3390/molecules28093969 2023
SW62079— 10.3390/molecules28093969 2023
HL6081— 10.3390/molecules28093969 2023
HL6081— 10.1039/c9ra08736b 2019
Caco-282— 10.3390/molecules28093969 2023
MCF-783— 10.3390/molecules28093969 2023
COLO-20592— 10.3390/molecules28093969 2023
LoVo99— 10.3390/molecules28093969 2023
HeLa1e+02— 10.3390/molecules28093969 2023
HT-291.1e+02— 10.3390/molecules28093969 2023
SW6201.1e+02— 10.3390/molecules28093969 2023
COLO-2051.1e+02— 10.3390/molecules28093969 2023
Ishikawa1.2e+02— 10.3390/molecules28093969 2023
HT-291.2e+02— 10.3390/molecules28093969 2023
MCF-71.3e+02— 10.3390/molecules28093969 2023
A5491.6e+02— 10.3390/molecules28093969 2023
HeLa1.6e+02— 10.3390/molecules28093969 2023
Caco-2—— 10.3390/molecules28093969 2023
Hep3B—— 10.3390/molecules28093969 2023
A549—— 10.3390/molecules28093969 2023
HCC38—— 10.3390/molecules28093969 2023

🧬 Cell Death Types (1)

Apoptosis high
«Microscopic analysis showed that ruthenium derivatives induce apoptosis in cancer cells.»