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Complex #4075 — Ru(2) [2]

2D Structure

Structure
⬇ MOL V3000

Info

ID4075
MetalRu
Oxidation state2
Charge2
Donor atoms{"N": 8}
Abbreviation2
SMILESCC(O)(CS(=O)(=O)c1ccc(F)cc1)C(=O)Nc1ccc(C#N)c(C(F)(F)F)c1.CC(O)(CS(=O)(=O)c1ccc(F)cc1)C(=O)Nc1ccc(C#N)c(C(F)(F)F)c1.c1cnc2c(c1)ccc1cccnc12.c1cnc2c(c1)ccc1cccnc12

TUCAN

C60H44F8N8O8RuS2/(1-83)(2-84)(3-47)(4-85)(5-45)(6-63)(7-48)(8-62)(9-50)(10-54)(11-56)(12-67)(13-45)(14-60)(15-55)(16-58)(17-51)(18-59)(19-45)(20-66)(21-57)(22-69)(23-61)(24-86)(25-68)(26-49)(27-70)(28-72)(29-46)(30-46)(31-52)(32-53)(33-101)(34-101)(35-64)(36-71)(37-102)(38-65)(39-46)(40-102)(41-107)(42-108)(43-119)(44-120)(45-93)(46-94)(47-56)(47-73)(48-55)(48-73)(49-75)(49-89)(50-58)(50-77)(51-59)(51-78)(52-60)(52-89)(53-76)(53-92)(54-57)(54-77)(55-83)(56-78)(57-80)(58-84)(59-85)(60-74)(61-68)(61-80)(62-63)(62-97)(63-103)(64-65)(64-79)(65-92)(66-67)(66-97)(67-103)(68-86)(69-70)(69-104)(70-98)(71-72)(71-104)(72-98)(73-87)(74-75)(74-81)(75-99)(76-79)(76-100)(77-88)(78-90)(79-82)(80-91)(81-105)(82-106)(83-109)(84-110)(85-111)(86-112)(87-90)(87-109)(88-91)(88-110)(89-107)(90-111)(91-112)(92-108)(93-95)(93-101)(93-119)(94-96)(94-102)(94-120)(95-107)(95-113)(96-108)(96-114)(97-127)(98-128)(99-121)(99-122)(99-123)(100-124)(100-125)(100-126)(101-129)(102-130)(103-129)(104-130)(109-131)(110-131)(111-131)(112-131)(115-129)(116-129)(117-130)(118-130)(119-131)(120-131)(129-131)(130-131)

Measurements (4)

Cell lineIC₅₀ dark (µM)IC₅₀ light (µM)DOIYear
LNCaP7114 10.1016/j.jinorgbio.2019.03.02... 2019
LNCaP7168 10.1016/j.jinorgbio.2019.03.02... 2019
PC-378 10.1016/j.jinorgbio.2019.03.02... 2019
PC-3 10.1016/j.jinorgbio.2019.03.02... 2019

🧬 Cell Death Types (1)

Apoptosis high
«The potential of these complexes to induce apoptosis in LNCaP cells was performed under light and dark conditions by Hoechst 33342 DNA staining and flow cytometry assay. ... the apoptotic rates induce...»