Info
| ID | 3616 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"N": 3} |
| Abbreviation | 1 |
| SMILES | Cc1ccc(C(C)C)cc1.O=C(/N=C(/[N-]c1ccccc1)Nc1ccccc1)c1cccs1.[Cl-] |
TUCAN
C28H28N3ORuS/(1-34)(2-44)(3-41)(4-30)(5-30)(6-30)(7-50)(8-40)(9-36)(10-42)(11-46)(12-43)(13-32)(14-45)(15-35)(16-33)(17-55)(18-38)(19-39)(20-29)(21-37)(22-31)(23-31)(24-29)(25-29)(26-31)(27-47)(28-57)(29-48)(30-50)(31-50)(32-35)(32-36)(33-35)(33-46)(34-44)(34-51)(36-52)(37-38)(37-48)(38-49)(39-47)(39-49)(40-42)(40-55)(41-44)(41-45)(42-56)(43-45)(43-51)(46-52)(47-48)(49-50)(51-58)(52-57)(53-57)(53-58)(53-59)(54-56)(54-59)(54-60)(55-61)(56-61)(58-62)(59-62)(61-62)
Measurements (3)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A549 | 1.8e+02 | — | 10.1021/acs.organomet.8b00702 | 2018 |
| HepG2 | — | — | 10.1021/acs.organomet.8b00702 | 2018 |
| Vero | — | — | 10.1021/acs.organomet.8b00702 | 2018 |
🧬 Cell Death Types (1)
Apoptosis
high
«The cell death mechanism of the active complexes 2 and 3 was found to be apoptosis as assessed by flow cytometry and staining methods.»