Info
| ID | 3360 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 2 |
| Donor atoms | {"N": 8} |
| Abbreviation | 2 |
| SMILES | FC(F)(F)c1ccc(-c2nc3c4cccnc4c4ncccc4c3[nH]2)cc1.c1cnc2c(c1)ccc1cccnc12.c1cnc2c(c1)ccc1cccnc12 |
TUCAN
C44H27F3N8Ru/(1-56)(2-28)(3-30)(4-43)(5-57)(6-36)(7-29)(8-41)(9-38)(10-39)(11-34)(12-40)(13-32)(14-31)(15-35)(16-33)(17-58)(18-44)(19-37)(20-61)(21-59)(22-42)(23-47)(24-60)(25-46)(26-45)(27-73)(28-30)(28-56)(29-44)(29-57)(30-48)(31-35)(31-60)(32-33)(32-55)(33-59)(34-41)(34-54)(35-50)(36-38)(36-48)(37-43)(37-58)(38-49)(39-40)(39-52)(40-53)(41-51)(42-47)(42-51)(43-49)(44-52)(45-46)(45-61)(46-53)(47-54)(48-62)(49-63)(50-66)(50-68)(51-70)(52-64)(53-65)(54-71)(55-67)(55-69)(56-74)(57-75)(58-76)(59-72)(60-79)(61-78)(62-63)(62-74)(63-76)(64-65)(64-75)(65-78)(66-69)(66-77)(67-68)(67-72)(68-79)(69-73)(70-73)(70-77)(71-80)(71-81)(71-82)(74-83)(75-83)(76-83)(77-83)(78-83)(79-83)
Measurements (13)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| MG-63 | 13 | — | 10.1002/cmdc.201300379 | 2014 |
| MDA-MB-231 | 16 | — | 10.1016/j.ejmech.2014.04.070 | 2014 |
| A549 | 20 | — | 10.1002/cmdc.201300379 | 2014 |
| MCF-7 | 32 | — | 10.1002/cmdc.201300379 | 2014 |
| A549 | 43 | — | 10.1038/srep19449 | 2016 |
| A549cisR | 48 | — | 10.1038/srep19449 | 2016 |
| HeLa | 55 | — | 10.1038/srep19449 | 2016 |
| MCF-7 | 74 | — | 10.1016/j.ejmech.2014.04.070 | 2014 |
| LO2 | 76 | — | 10.1038/srep19449 | 2016 |
| HK-2 | 80 | — | 10.1002/cmdc.201300379 | 2014 |
| A549R MCTSs | 96 | — | 10.1038/srep19449 | 2016 |
| EC-1 | — | — | 10.1016/j.ejmech.2014.04.070 | 2014 |
| HaCaT | — | — | 10.1016/j.ejmech.2014.04.070 | 2014 |
🧬 Cell Death Types (1)
Apoptosis
high
«A double-staining Annexin V/PI apoptosis kit and flow cytometry were used to investigate the nature of A549R cell death induced by complex 4. The results are shown in Fig. 7b. At a concentration as lo...»