Info
| ID | 100 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"O": 1, "N": 2} |
| Abbreviation | 3 |
| SMILES | COc1ccc(/C([O-])=N/N=C\c2c3ccccc3cc3ccccc23)cc1.[Cl-].c1ccccc1 |
TUCAN
C29H23N2O2Ru/(1-24)(2-25)(3-35)(4-32)(5-26)(6-27)(7-28)(8-29)(9-36)(10-49)(11-40)(12-30)(13-42)(14-31)(15-38)(16-39)(17-50)(18-41)(19-34)(20-33)(21-37)(22-50)(23-50)(24-25)(24-26)(25-27)(26-28)(27-29)(28-29)(30-31)(30-35)(31-32)(32-43)(33-43)(33-46)(34-36)(34-37)(35-45)(36-46)(37-39)(38-40)(38-48)(39-47)(40-51)(41-42)(41-48)(42-51)(43-45)(44-45)(44-47)(44-49)(46-47)(48-52)(49-53)(50-56)(51-56)(52-54)(52-55)(53-54)(53-57)(54-57)(56-57)
Measurements (4)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| MDA-MB-231 | 11 | — | 10.1039/c6qi00197a | 2016 |
| HepG2 | 14 | — | 10.1039/c6qi00197a | 2016 |
| HeLa | 14 | — | 10.1039/c6qi00197a | 2016 |
| NIH-3T3 | 2.5e+02 | — | 10.1039/c6qi00197a | 2016 |
🧬 Cell Death Types (1)
Apoptosis
high
«Furthermore, the results of AO–EB, Hoechst 33258 and flow cytometry analyses reveal that these complexes induce cell death only through apoptosis.»